venofer dosing calculator

All Rights Reserved. Pediatric Patients (2 Years of Age and Older). Severe adverse reactions including circulatory failure (severe hypotension, shock including in the context of anaphylactic reaction) may occur in pregnant women with parenteral iron products (such as Venofer) which may cause fetal bradycardia, especially during the second and third trimester. Am J Hosp Pharm. PDF Injectafer (ferric carboxymaltose injection) - Food and Drug Administration Equations used: 1] Calculation of the Total Iron Deficit: Total iron deficit [mg] = body weight [kg] x (target Hb-actual Hb) [g/dl] x 2.4 + depot iron [mg]. Avoid or Use Alternate Drug. Recommended starting dose 1 Aranesp is dosed at 2.25 mcg/kg SC QW or 500 SC Q3W 1 (SC = subcutaneous) Before initiating 1: Evaluate iron status; administer supplemental iron therapy as needed Correct or eliminate other causes of anemia Initiate 1: Only when Hb < 10 g/dL In the text below the tool there is more information on how the iron deficit is calculated. Venofer has not been studied in patients younger than 2 years old. Parenteral iron product is iron sucrose (C = 20 mg elemental iron/mL). Drug class: Iron products. Data from Ferrlecit postmarketing spontaneous reports indicate that individual doses exceeding 125 mg may be associated with a higher incidence and/or severity of adverse events. When iron sucrose was administered at deliberate overdoses to rabbit dams (up to 215 mg/kg/day) marked fetal/placental iron overload was noted. Applies only to oral form of both agents. Reactions have occurred following the first dose or subsequent doses of Venofer. Intravenous iron-dextran: therapeutic and experimental possibilities [in German] Schweiz Med Wochenschr. Administer Venofer early during the dialysis session (generally within the first hour). Parenteral iron dextran therapy. Modify Therapy/Monitor Closely. PDF Iron Sucrose: Guidelines for Administration Document Type: Guideline Do not mix iron sucrose with other medications or TPN solution. Minor/Significance Unknown. We first individually analyzed 5 clinical studies, averaging the total iron deficit across all patients utilizing a . Parenteral iron dextran therapy: a review. Adding plans allows you to compare formulary status to other drugs in the same class. Generic name: IRON SUCROSE 20mg in 1mL On the other hand, slow decreases, such as that in chronic occult gastrointestinal bleeding are often difficult to diagnose. Do not dilute to concentrations below 1 mg/mL [see How Supplied/Storage and Handling [16.2].) This document does not contain all possible drug interactions. David McAuley, Pharm.D. Human studies not conducted. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. Coadministration of ciprofloxacin with multivalent cation-containing products may reduce the bioavailability of ciprofloxacin by 90%. Applies only to oral form of both agents. Please confirm that you would like to log out of Medscape. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. The primary endpoint was the proportion of patients with . Either increases effects of the other by pharmacodynamic synergism. Anemias. 5. commonly, these are "non-preferred" brand drugs. Use Caution/Monitor. Monitor Closely (1)cimetidine will decrease the level or effect of iron sucrose by increasing gastric pH. Share cases and questions with Physicians on Medscape consult. Dosing Administration & Considerations . lansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. 1974 Jun;31(6):592-5. Recommended dosage for patients weighing less than 50kg (110lb): Give Injectafer in March 2, 2015 [IRON SUCROSE REQUIREMENT CALCULATION FOR SEVERE ANEMIA] DPMU Anantapuramu | National Health Mission 1 Formula for calculating the required dose of Iron sucrose 2.4 X Pre-pregnancy Weight in Kgs X Hb% deficit{11-actual Hb%} in mgs Plus Iron required to replenish the iron stores = 500mg Prepregnancy Weight = 45 kgs . Dosing Considerations (8-10) Maximum single dose of iron sucrose in all other patients is 300 mg every week. Avoid or Use Alternate Drug. The iron deficit estimation is based on the Ganzoni formula: Total iron deficit (mg) = Weight in kg x (Target Hb - Actual Hb in g/dL) x 2.4 + Iron stores. elemental iron (mg/ml) in the product being used: Where C= Use Caution/Monitor. Minor (1)gymnema decreases levels of iron sucrose by inhibition of GI absorption. Applies only to oral form of both agents. The dosage of Venofer is expressed in mg of elemental iron. Monitor Closely (1)didanosine will decrease the level or effect of iron sucrose by increasing gastric pH. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. Venofer Injection Dosage Guide - Drugs.com Venofer (iron sucrose) dose calculator | Calculosaurus.com This iron deficiency calculator determines the iron deficit based on patient weight, hemoglobin and iron stores to prepare for iron replacement. Avoid or Use Alternate Drug. Written by ASHP. Medically reviewed by Drugs.com. Ren Fail. Use Caution/Monitor. Results: Twelve children (6 females) aged 1.2-14 years (median age 8.9 years) received at least one dose of . You will have to pay for your IV iron. Applies only to oral form of both agents. Monitor Closely (1)sodium citrate/citric acid will decrease the level or effect of iron sucrose by increasing gastric pH. IDA symptoms vary, may not be specific and include tiredness, weakness, shortness of breath. Use Caution/Monitor. Applies only to oral form of both agents. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or Use Caution/Monitor. Applies only to oral form of both agents. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. The factor 2.4 comes about from the calculation that the total iron content of hemoglobin is 0.34%, the blood volume accounts for 7% . iron sucrose decreases levels of penicillamine by inhibition of GI absorption. You may need extra iron because of blood loss during kidney dialysis. After total replacement dose completed, need for ongoing IV doses should be re-assessed monthly. 0.5 mg/kg/min (0.005 mL/kg/min) Maximum infusion rate (if tolerated) Increase to 8 mg/kg/min (0.08 mL/kg/min) Monitor the patient's vital signs throughout the infusion. May increase risk of hypotension. All Rights Reserved. Oral and parenteral products - see background option for oral products. Applies only to oral form of both agents. Use Caution/Monitor. Burns DL, Mascioli EA, Bistrian BR. Applies only to oral form of both agents. Minor/Significance Unknown. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. Modify Therapy/Monitor Closely. Applies only to oral form of both agents. 300-500 mg Iron Sucrose in NS 250 mL administered over three (3) hours; may repeat as needed in 3-7 days to reach 1 gm. iron sucrose increases levels of calcium carbonate by enhancing GI absorption. Applies only to oral form of both agents. FERAHEME Dosing & Administration - Feraheme FERAHEME has flexible dosing for your patients FERAHEME flexible scheduling gives your patients the freedom to receive the iron they need as early as 3 days apart 1 FLEXIBLE DILUTION OPTIONS 1 Dilute full contents of vial (17 mL) in 50 mL to 200 mL of: 0.9% NaCl, or 5% dextrose STORAGE 1 and formulary information changes. Use Caution/Monitor. Iron metabolism needs to be balanced and bleeding, the major cause of iron deficiency (for instance in menstruation in females and chronic occult gastrointestinal bleeding) needs to be addressed. The recipient will receive more details and instructions to access this offer. Bhowmik D, Modi G, Ray D, Gupta S, Agarwal SK, Tiwari SC, Dash SC. The dosage of iron sucrose is expressed in mg of elemental iron. esomeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. * Calculators are available in UpToDate to determine ideal body weight and lean body weight. Serious - Use Alternative (1)iron sucrose decreases levels of ciprofloxacin by inhibition of GI absorption. PDF Protocol for the use of Intravenous Iron Dextran (CosmoFer To provide clinicians with evidence-based guidance for iron therapy dosing in patients with iron deficiency anemia (IDA), we conducted a study examining the benefits of a higher cumulative dose of intravenous (IV) iron than what is typically administered. This site complies with the HONcode standard for trust- worthy health information: verify here. Human studies not conducted. Auerbach M, Witt D, Toler W, Fierstein M, Lerner RG, Ballard H. Clinical use of the total dose intravenous infusion of iron dextran. Use Caution/Monitor. Avoid or Use Alternate Drug. Here are the steps to follow for using this drug dosage calculator: First, enter the value of your Weight and choose the unit of measurement from the drop-down menu. A healthcare provider will give you this injection. Minor/Significance Unknown. Serious - Use Alternative (1)iron sucrose decreases levels of mycophenolate by inhibition of GI absorption. )If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Use Caution/Monitor. iron sucrose decreases levels of levofloxacin by inhibition of GI absorption. iron sucrose decreases levels of thyroid desiccated by inhibition of GI absorption. Iron Injection Administration | INJECTAFER HCP Applies only to oral form of both agents. iron sucrose decreases levels of methyldopa by inhibition of GI absorption. 1995 Mar-Apr;11(2):163-8. Applies only to oral form of both agents. Compare formulary status to other drugs in the same class. iron sucrose decreases levels of minocycline by inhibition of GI absorption. iron sucrose decreases levels of deferiprone by enhancing GI absorption. The dose of Ferinject is based on calculation of ideal body weight and calculation of iron deficit using the Ganzoni formula. Give each dose as 15 mg/kg body weight for a total cumulative dose not to exceed 1500 mg of iron per course. nizatidine will decrease the level or effect of iron sucrose by increasing gastric pH.

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